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In Vivo Antibodies: Precision and Physiological Relevance

In vivo research demands antibodies of the highest purity and functional integrity to ensure reproducible results in complex biological systems. Unlike standard in vitro reagents, in vivo grade antibodies are specifically engineered to be low in endotoxins, pathogen-free, and devoid of preservatives like sodium azide. These characteristics are essential to prevent non-specific immune activation and maintain physiological relevance. By utilizing high-affinity clones from industry leaders like Ichorbio, Assay Genie, and MedChem Express, researchers can effectively perform functional studies, including cellular depletion and receptor blockade.

Biosimilars: High-Fidelity Tools for Comparative Research

Research-grade biosimilars are indispensable tools for benchmarking and therapeutic modeling. These monoclonal antibodies are synthesized to match the sequences of innovator biologics, providing highly characterized reagents for preclinical investigations. Our portfolio features biosimilars that undergo rigorous quality control for binding affinity and biological activity, ideal for assay development and in vivo synergy studies.

Important: These reagents are developed solely for research use (RUO).

A specialist manufacturer of high-quality antibodies designed specifically for in vivo research. Ichorbio is dedicated to developing and supplying antibody solutions that enable scientists that work at the forefront of immuno-oncology, infectious disease, and fundamental immunology to get accurate results.

FEATURED PRODUCT CATEGORIES

Isotype Controls	Anti-Human Antibodies	Research Biosimilars
In Vivo Antibodies	Research Panels	Auxiliary Reagents

RESEARCH BIOSIMILARS

Comprehensive Research Biosimilars

Transform your therapeutic development process with our extensive portfolio of research-grade biosimilars. Whether you're developing new checkpoint inhibitors or exploring novel combination therapies, our validated antibodies provide the reliable benchmarking tools you need.

IN VIVO ANTIBODIES

Validated in Vivo Solutions

Move your research forward with our selection of in vivo antibodies, specifically developed for preclinical research. Each batch undergoes rigorous testing and is provided with comprehensive documentation.

ISOTYPE CONTROLS

Essential Controls for Validated Research

Success in therapeutic development demands reproducible results. Our isotype controls are manufactured to the same exacting standards as our research antibodies, with low endotoxin levels suitable for in vivo applications.

In Vivo Functional Grade Antibodies

Low and Ultra-Low Endotoxin Antibodies

Assay Genie In Vivo Functional Grade Antibodies are ideal for scientists who need ultra-pure, low-endotoxin antibodies for demanding applications, including in vivo mouse studies, in vitro functional assays, and 3D Organoid platforms.

Using a proprietary multi‑step purification process, these antibodies are free from preservatives, stabilisers, and carrier proteins and have up to >98% purity. The range includes low‑endotoxin (<1.0 EU/mg), ultra‑low endotoxin (<0.5 EU/mg), and matched isotype control antibodies as well as biosimilar & bispecific antibodies for immune modulation and therapeutic development.

Low Endotoxin	Ultra Low Endotoxin	Bispecifics	Biosimilars
High purity and low endotoxin levels (≤ 1.0 EU/mg) antibodies for in vivo functional studies.	With ≤0.5 EU/mg endotoxin levels, and Pathogen-free (IDEXX Impact tested).	Antibodies designed for dual-target engagement and immune modulation.	In vivo grade antibodies engineered to replicate reference biologics.

Industry leading quality

High Purity In Vivo mAbs

Key features

Applications

Validation Data

Popular In Vivo mAbs

Inhibitory Antibodies

MedChemExpress (MCE) Inhibitory Antibodies are research-grade biosimilar antibodies that have the same bioactive component as the original therapeutic antibodies. Biosimilar makes it possible to study the biological effects of a drug.

These antibodies bind specifically to target cells or proteins, either stimulating the immune system to attack the malignant tumor cells or preventing tumor growth by blocking specific cell receptors. Target proteins include CD20, HER2, EGFR, VEGFR, TNF-alpha, etc. MCE Inhibitory Antibodies have been extensively used in the most popular research fields, such as cancer, immunology and infection.