Xpedite Diagnostics develops rapid nucleic extraction kits for molecular for infectious disease research, genomics workflows and molecular diagnostics.

A defining feature of Xpedite’s extraction platforms is the Reverse Purification technology.

Unlike traditional nucleic acid extraction systems where DNA or RNA binds to magnetic beads or silica columns, the Xpedite approach works by binding impurities such as proteins and cell debris to magnetic particles while leaving nucleic acids free in the lysate.

This approach offers several advantages:

• Higher nucleic acid recovery

• Reduced risk of sample loss

• Simplified workflows with fewer steps

• Compatibility with multiple sample types

• Reduced need for complex instrumentation

For research laboratories handling diverse samples, this flexibility can significantly streamline molecular workflows.

These kits are compatible with common downstream techniques such as PCR, RT-qPCR and next-generation sequencing (NGS).

Key Products: 

SwiftX™ DNA is a versatile nucleic acid extraction kit designed for the rapid isolation of genomic and mitochondrial DNA from a wide range of biological samples including human and animal cells, bacteria, parasites, fungi and viruses. The kit enables streamlined DNA extraction workflows and produces PCR-ready nucleic acids in just a few minutes.

The technology is based on Xpedite’s proprietary reverse purification method, where magnetic particles bind impurities such as proteins and cellular debris, leaving DNA free in solution. This approach improves nucleic acid recovery and minimizes sample loss compared with conventional binding-based extraction methods.

Key Features:

• DNA extraction in 5–15 minutes

• Magnetic bead-based reverse purification

• No centrifugation required

• Broad compatibility with multiple sample types

SwiftX™ Virus is designed for the fast extraction of viral nucleic acids from clinical and research samples such as plasma and serum. The workflow enables the preparation of DNA or RNA suitable for downstream molecular assays including RT-qPCR and multiplex PCR.

The kit is optimized for rapid viral detection workflows, enabling nucleic acid extraction in only a few minutes while maintaining high analytical sensitivity.

Key Features:

• Rapid viral DNA/RNA extraction

• One-tube workflow

• Minimal equipment required

SwiftX™ Blood Genomic – Rapid Genomic DNA Extraction from Whole Blood

SwiftX™ Blood Genomic is a rapid nucleic acid extraction kit designed for the isolation of high-quality genomic DNA directly from whole blood samples. The kit enables efficient DNA extraction from 10 µL up to 1 mL of blood and delivers PCR-ready genomic DNA in less than 15 minutes, significantly simplifying blood-based molecular workflows.

The kit is optimized for research laboratories working with human or animal blood samples and supports a broad range of downstream molecular biology applications. The extracted DNA can be used for real-time PCR, isothermal amplification, microarray analysis, capillary electrophoresis and next-generation sequencing (NGS).

The protocol includes a rapid red blood cell lysis step followed by purification based on Xpedite’s proprietary magnetic bead technology, enabling efficient recovery of high-molecular-weight DNA suitable for advanced genomic analyses.

Key Features:

• Rapid genomic DNA extraction from whole blood

• Compatible with 10 µL to 1 mL blood samples

• DNA extraction in under 15 minutes

• High-molecular-weight DNA suitable for sequencing workflows

SwiftX™ cfDNA  – Cell-Free DNA Extraction

SwiftX™ cfDNA is optimized for the extraction of circulating cell-free DNA (cfDNA) from plasma, serum and urine samples, supporting liquid biopsy and oncology research workflows. The protocol enables the isolation of high-quality cfDNA in under 15 minutes and is compatible with downstream technologies such as qPCR, ddPCR and next-generation sequencing.

The kit is particularly useful for applications such as cancer research, prenatal testing (NIPT) and infectious disease monitoring.

Key Features:

• cfDNA extraction in <15 minutes

• Compatible with plasma, serum and urine

• Suitable for liquid biopsy workflows

• High sensitivity for low-abundance DNA

SwiftX™ DNA Water – Rapid Environmental DNA Extraction from Water Samples

SwiftX™ DNA Water is designed for the rapid extraction of environmental DNA directly from water samples. The kit enables researchers to isolate DNA from microorganisms and other biological material present in environmental water samples such as freshwater, marine water or wastewater.

The system is particularly useful for laboratories working in environmental genomics, biodiversity monitoring, microbial ecology and water quality studies. 

SwiftX™ DNA Water enables fast extraction protocols and produces PCR-ready DNA suitable for molecular detection and sequencing applications.

Key Features:

• Rapid DNA extraction from environmental water samples

• Suitable for environmental DNA research and biodiversity monitoring

• Efficient removal of environmental inhibitors

• Magnetic bead-based reverse purification technology

Magnetic Separation Racks for SwiftX™ Extraction Workflows

To further simplify nucleic acid extraction workflows, magnetic racks compatible with SwiftX™ extraction kits are also available. 

Magnetic racks are compatible with common laboratory formats and can be used with standard microcentrifuge tubes and PCR tubes, making them suitable for a wide range of molecular biology workflows in academic and biotechnology laboratories.

Applicable to:

• Tubes of any reasonable size
• Various types of liquids, even highly viscous samples
• Reliable separation of magnetic particles or para-magnetic particles

Key Advantages:

• Optimized for magnetic bead-based nucleic acid extraction

• Rapid magnetic separation of beads

• Compatible with 1.5 mL and 2 mL microcentrifuge tubes

• Compact design for benchtop workflows

• Ideal for use with SwiftX™ DNA, Virus, cfDNA, Blood Genomic and DNA Water kits

Applications:

• Virology
• African Swine Fever
• Bacteriology
• Wastewater Epidemiology and Microbiome
• Parasitology
• Schistosomiasis
• Leishmaniasis
• Mycology
• Oncology

Xpedite Diagnostics is available through DBA Italia.

Researchers, academic laboratories and biotechnology companies interested in these solutions are invited to contact our team for additional information, technical support or to request a quotation.